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The Tottenham defender found the net on two occasions as Tottenham extended their unbeaten run on the road in the top division and handed Everton their first defeat at their new home.

Everton were unbeaten in their last five matches at their new ground at the dockside location, having departed their historic home behind after 133 years at the conclusion of the previous campaign.

But Spurs captain the Dutchman struck twice from corners in the opening 45 minutes to put their impressive record at risk, and they were unable to turn it around before the midfielder - set up by ex-Everton forward Richarlison - headed home a final goal to seal the victory.

The Everton defender believed he had equalized the tally five minutes after the defender's opener, glancing a bullet header past Guglielmo Vicario from an Everton corner.

The Portuguese striker, in the meantime, missed a number of opportunities, while the Italian goalkeeper made a succession of excellent saves to ensure Tottenham went five matches on the road unbeaten in the English top flight.

But the video assistant referee stepped in, advising the match official to check the goal on the pitchside monitor and the official ruled that Jack Grealish and the attacker were in an illegal position and had interfered with the Tottenham goalkeeper.

The win moves Thomas Frank's side up to third in the division, five points off north London rivals and table-toppers the Gunners.

Everton stay 14th and sit six points clear of the drop zone.

Tottenham analysis: The defender excels in role at both ends of pitch

After a drab weekday display in the European competition against the French side, where they managed a mere two shots on target, Frank chose the French striker in attack instead of ex-Everton forward Richarlison.

The summer signing was failed to influence the game before being replaced for the substitute after 60 minutes on the field, but it emerged he wasn't needed in the final outcome.

Centre-back the Dutchman transformed into an offensive threat to be feared.

Spurs' first goal came from a cleverly executed corner routine, with Rodrigo Bentancur heading the ball toward the six-yard box for an free Van de Ven to score.

And Ven de Ven - stepping up as captain in Cristian Romero's unavailability - added his next goal in added time as he rose above Jordan Pickford to head home.

Van de Ven was equally outstanding in defence, combining effectively with Kevin Danso as the pair handled superbly with the 34 crosses sent their way by Everton.

Everton analysis: Toffees lacking striker's instinct

Everton's recent stadium had been a fortress, but it seems the freshness may have worn off somewhat and fans headed to the exits after the midfielder's final goal for Tottenham.

The break in Everton's winning streak at home will not be a major concern for David Moyes, but their attacking woes will be.

Beto and the other striker - the Everton's pair of established centre-forwards - had netted just one league goal combined before the weekend's match.

And they were failed to add to that miserable tally on a damp and dreary evening on in Liverpool.

The striker's form was summed up when he chose to overhead kick a golden opportunity from close range, even with having room and opportunity to reposition for a simpler attempt that would have tested Vicario.

Barry, too, failed to make an impact after coming on for the starter in the 65th minute.

It wasn't for a lack of chance. Most of the home side's offensive moves came through Grealish and the forward, who tirelessly delivered dangerous crosses into the Spurs box.

Upcoming fixtures for these two sides?

The Toffees: The team head to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.

Tottenham: The London club travel to St James' Park on Wednesday, 29 October for their fourth-round League Cup match against the Magpies.